2 edition of Synthesis of polyimidazole ligands and their copper complexes. found in the catalog.
Synthesis of polyimidazole ligands and their copper complexes.
Timothy Charles Higgs
Manchester thesis (Ph.D.), Department of Chemistry.
|Contributions||Department of Chemistry.|
|The Physical Object|
|Number of Pages||511|
Novel nitrogen ligands based on imidazole derivatives and their application in asymmetric catalysis Filip Buresˇ,a,* Toma´sˇ Szotkowski,a Jirˇı´ Kulha´nek,a Oldrˇich Pytela,a Miroslav Ludwiga and Michal Holcˇapekb aDepartment of Organic Chemistry, University of Pardubice, na ´m.Cˇ s. Legiı , Pardubice , Czech Republic. Organocopper compounds in organometallic chemistry contain carbon to copper chemical bonds. Organocopper chemistry is the science of organocopper compounds describing their physical properties, synthesis and reactions. They are reagents in organic chemistry.. The first organocopper compound, the explosive copper(I) acetylide Cu 2 C 2 (Cu-C≡C-Cu), was . A complex ion typically consist of a transition metal cation bounded to ligands which can be neutral molecules or ions. The number of ligands attached to the transition metal ion is known as the.
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Functional mimics of copper enzymes. Synthesis and stereochemical properties of the copper(II) complexes of a trinucleating ligand derived from l-histidine. Tetrahedron: Asymmetry10 (2), DOI: /S(98)Cited by: Synthesis, X-ray Crystal Structure, and Redox and Electronic Properties of Iron(III)−Polyimidazole Complexes Relevant to the Metal Sites of Iron Proteins.
Inorganic Chemistry42 (6), Cited by: Synthesis and Properties of Dinuclear Copper(II) Complexes Containing Dinucleating Ligands with Imidazole Nitrogen and Two Exogenous Bridging Ligands.
Bulletin of the Chemical Society of Japan67 (9), DOI: /bcsjCited by: 6. Copper(II) complexes of a series of di- tri- and tetraimidazole ligands have been synthesized and their crystal structures determined using X-ray diffraction.
A variety of coordination modes and geometries are observed, giving insight into the factors which control the stability of copper(II) by: Several copper(II) complexes containing new tripodal polyimidazole ligands have been synthesized and characterized by X-ray crystallography, UV-vis and EPR spectroscopies, and cyclic voltammetry.
A novel single pot synthesis of binuclear copper(II) complexes of macrocyclic and macroacyclic compartmental ligands: Structures and magnetic properties. Journal of Molecular Structure(), Cited by: General procedure for the synthesis of complexes: The metal precursor Cu(OAc) 2 H 2 O ( g) and biphenylazo ligands (HL 1 –HL 5) ( g) were taken in 20 ml of ethanol.
The reaction mixture was heated under reflux for 3 h, and then cooled to room temperature and solids, if any were filtered by: 3. The ligands and the corresponding copper and cobalt complexes prepared in the current study were tested in terms of their in vitro cytotoxicity against cell cancer cells lines, including human lung cancer (A), breast adenocarcinoma (MCF-7) and human embryonic kidney (HEK) cells using a standard MTT assay (Mosmann, ).Cited by: 1.
The base of square pyramid is formed by copper linked to four N atoms of four imidazole ligands and one of the chlorine atoms is located at the apex of the pyramid.
The structure of 2 is similar to the structure of its bromide analog  and of two Cu (II) complexes with unsubstituted imidazole , .Cited by: Chemistry. The ligands L1, L2 and L3 have all been published previously. 55 Transition metal complexes of these ligands were generally formed from anhydrous metal salts in nonprotic solvents in an inert atmosphere glove box.
Mn 2+, Fe 2+, and Co 2+ divalent complexes are often air sensitive and must be protected from oxygen. Additionally, it is known Cited by: Two novel metal-organic coordination complexes of copper(II) and silver(I) with 1,3,4-thiadiazole-based ligands HL1 [N-(5-methyl-1,3,4-thiadiazol.
The results showed that its building block is made of one partially-deprotonated H 2 pdc and one fully-deprotonated pdc ligands that act as bridging ligands between two copper(II) ions that axial positions of copper ions are occupied with two water molecules.
A novel type of cyclic P,N-ligands, pyridyl containing phospholanes, has been synthesized in a moderate yield by the reaction of primary phosphines with 1,4-dichlorobutane in a. The present work reports the synthesis and structural elucidation of two dithiocarbazate ligands derived from 4,6-diacetylresorcinol (H 3 L 1) and (H 3 L 2) and two Cu(II) complexes, [Cu(μ-HL 1)] 2 (1) and [Cu(μ-HL 2)] 2 (2).
These compounds were studied by the Density Functional Theory with which it was possible to identify their lowest energy conformations. Synthesis of some polyimidazole ligands related to zinc enzymes Article (PDF Available) in Journal of the American Chemical Society (16) August with 41.
Lysine based Schiff bases and their complexes 32 with La, Co, Fe, show bacteriostatic activity to B. subtilis, and S. aureus. Zn (II), Cd (II), Ni (II) and Cu (II) complexes with furfural and semicarbazide33, and with furfurylidene diamine 34 Shiff bases show antibacterial by: 4.
Preparation and identification of new Azo (methyl-xanthine) ligands and their transition metal complexes Article (PDF Available) in International Journal.
Methods of synthesis are presented followed by studies focusing on their potential application as anti-cancer agents and more recent investigations into their potential as therapeutics for Alzheimer's by: Synthesis of 4 amino(pyridyl)-4H-1,2,4-triazolethiol (ligand) A mixture of isonicotinic acid (1 g) ( mol) and ( g) ( mol) from potassium hydroxide, was dissolved in (10 ml) ethanol.
After mixture was dissolved then (2 ml) ( mol) Cited by: Three new 6-methyloxo-1,2-dihydroquinolinecarbaldehyde-thiosemicarbazones-Nsubstituted pro-ligands and their Cu(II) complexes (1, -NH2; 2, -NHMe; 3, -NHEt) have been prepared and characterized.
In both the X-ray structures of 1 and 3, two crystallographically independent complex molecules were found that differ either in the nature of weakly metal. The absorption bands of the palladium(II) and copper(I) complexes are red-shifted relative to the free ligands and show enhanced molar absorptivity.
The complexes all display strong MLCT absorptions in the visible spectrum, the palladium(II) compounds are deep purple (λ max = ∼– nm), while the copper(I) complexes are red-brown. A new copper(II) complex with formulae of [Cu(buobb)2](pic)2, where buobb stands for the ligand of 1,3-bis(1- butylbenzimidazolyl)oxopropane and pic represents 2,4,6-trinitrophenol, has been synthesized and characterized by elemental analyses, molar conductivity, IR, UV-Vis spectra measurements, and cyclic voltammetry.
The crystal structure of the copper(II) complex Cited by: 8. 1H-NMR. Antibacterial activity of the ligands and their metal complexes were tested against selected bacteria by disc diffusion method.
Keywords: 1,Phenanthroline, imidazole, complex, antibacterial activity. INTRODUCTION 1,Phenanthroline (phen) and its derivations play important roles for supramolecular assembliesAuthor: Kabeer A Shaik, Azeem Ahmed. These complexes exhibit several close parallels with the CuB site of the enzymes.
More biomimetically accurate 4-tethered bis (imidazole)thioether ligands and their copper complexes that incorporate the ligand set of the CuB site of the copper hydroxylase enzymes have been prepared and : $ Part of the success of the BOX and PyBOX motifs lies in their convenient one step synthesis from malononitrile and dipicolinic acid, which are commercially available at low expense.
Chirality is introduced with the amino alcohols, as these are prepared from amino acids and. Furthermore, the interaction abilities of the Cu(II) complexes with HSA/DNA were greater as compared to their corresponding ligands. Interestingly, C1 – C3, particularly C3, exhibited more cytotoxicity toward HeLa cells compared to normal HL cells and three other tumor cell lines (Hep-G2, NCI-H, and MGC).Cited by: 1.
The stability of a chelate complex depends on the size of the chelate rings. For ligands with a flexible organic backbone like ethylenediamine, complexes that contain five-membered chelate rings, which have almost no strain, are significantly more stable than complexes with six-membered chelate rings, which are in turn much more stable than complexes with four- or.
About this book This comprehensive reference and handbook covers in depth all major aspects of the use of N-heterocyclic carbene-complexes in organic synthesis: from the theoretical background to characterization, and from cross-coupling reactions to olefin metathesis.
Herein, we report the synthesis, molecular structures and bioevaluation of two different cationic copper(II) complexes with the third generation quinolone antibacterial agent levofloxacin (lvx) and 2N-substituted ligands 2,2′-dipyridylamine (bipyam) and bathophenanthroline (BPhen).The molecular structures of [Cu(lvx)(bipyam)Cl] + (1) and [Cu(lvx)(BPhen)Cl] + (2) exhibit distorted Cited by: 1.
icity activities of the organic ligands and their complexes were evaluated against several cancer cell lines, including MCF-7, A and HEK cells. The copper complexes of the organic ligands bear-ing a phenyl or allyl moiety at their N(3) position together with a piperidine substituent at the This Account describes the synthesis, structural and spectroscopic characterization, and reactivity studies of M–O 2 complexes bearing tetraazamacrocyclic n-TMC ligands, where M = Cr, Mn, Fe, Co, and Ni and n = 12, Cited by: These complexes contain a central atom or ion, often a transition metal, and a cluster of ions or neutral molecules surrounding it.
Ligands are ions or neutral molecules that bond to a central metal atom or ion. Ligands act as Lewis bases (electron pair donors), and the central atom acts as a Lewis acid (electron pair acceptor). Ligands have at. Schiff base are used as intermediates for the synthesis of amino acids or as ligands for Preparation of metal complexes having a series of different structures.
A Schiff base behaves as a Flexi-dentate ligand and commonly co-ordinates through the O atom of the. A transition metal-alkyl complex with 18 e-'s dictates that all the orbitals are in their full capacity, and there is no interaction that can occur with the beta-hydrogen and transition metal center.
Another way is to utilize stable alkyl ligands that do not contain beta-hydrogens and cannot undergo elimination. Synthesis and Cytotoxic Activity Evaluation of New Cu(I) Complexes of Bis(pyrazolyl) Acetate Ligands Functionalized with an NMDA Receptor Antagonist by Maura Pellei 1, Luca Bagnarelli 1, Lorenzo Luciani 1, Fabio Del Bello 2,*, Gianfabio Giorgioni 2, Alessandro Piergentili 2, Wilma Quaglia 2, Michele De Franco 3, Valentina Gandin 3.
In chemistry, a macrocyclic ligand is a macrocycle with a ring size of at least nine (including all hetero atoms) and three or more donor sites. Classic examples are crown ethers and porphyrins. Macrocyclic ligands exhibit particularly high affinity for metal ions.
Metals in medicine and in food. Synthetic coordination compounds with active drugs as ligands and innovative strategies for their delivery in the tissues. The synthesis of platinum group metal complexes with pyrimidine and purine derivatives, and non-steroidal anti-inflammatory drugs (NSAIDs) as ligands has acquired new impetus in the past decade.
Preparation and Identification of a Copper (I) Complex (Andrew W. Platt). Synthesis and Characteristics of a Metal Hydride Complex (Andrew W. Platt). Reactivity of Triphenylphosphine and Its Oxide Towards CuCl 2 (Paul F.
Kelly and Martin B. Smith). Synthesis of a Thermochromic Copper Complex (Iain A. Smellie). The Synthesis of Sterically Demanding Ligands and Examples of Their Copper Complexes by Ryan D.
Rieth Submitted to the Department of Chemistry on Aug in Partial Fulfillment of the Requirements for the Degree of Master of Science in Chemistry Abstract Conditions for promoting the Pd-catalyzed arylation of (N-pyrrolyl)zinc derivatives.
In coordination chemistry, a transition metal NHC complex is a metal complex containing one or more N-heterocyclic carbene ligands. Such compounds are the subject of much research, in part because of prospective applications in homogeneous catalysis.
One such success is the second generation Grubbs catalyst. Copper(I) Complexes of Phosphines, Functionalized Phosphines and Phosphorus Heterocycles is a comprehensive guide to one of the most widely used and extensively studied metals: copper.
The numerous practical applications of copper compounds are discussed, including homogeneous and heterogeneous catalysis and their use as fungicides, pesticides, pigments. Recently, much effort has been spent by our group and others to elucidate the mechanisms of the coupling processes that form C–N, C–O, and C–C bonds catalyzed by copper complexes of neutral, dative ligand, such as the Ullmann amination, 14 the Ullmann biaryl ether formation, 15 the Goldberg reaction, 16 and the Hurtley reaction.
17 The mechanisms of these Cited by: Organometallic complexes of precious metals such as iridium and ruthenium can be strongly luminescent, theoretically making them ideal for organic LEDs and dye-sensitised solar scarcity and cost, however, makes widespread use impractical. But now researchers in the US have shown how designer copper complexes can end the need for precious metals.